The following information is a summary about Penlac. It is not intended to replace a doctor's instructions.

Penlac USES
Penlac (ciclopirox) topical solution is used along with regular nail trimming to treat fungal infections of the fingernails and toenails (an infection that may cause nail discoloration, splitting and pain). Ciclopirox is in a class of medications called antifungals. It works by stopping the growth of nail fungus.

Penlac DIRECTIONS
Ciclopirox comes as a solution to apply to nails and the skin immediately surrounding and under the nails. It is usually applied once a day. To help you remember to use ciclopirox, apply it around the same time every day, usually at bedtime. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use ciclopirox exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor. Ciclopirox is used to improve the condition of nails, but may not completely cure nail fungus. It may take 6 months or longer before you notice that your nails are getting better. Continue to use ciclopirox daily as directed. Do not stop using ciclopirox without talking to your doctor. Ciclopirox topical solution will work best if you trim your nails regularly during your treatment. You should remove all loose nail or nail material using a nail clipper or nail file before you begin treatment and every week during your treatment. Your doctor will show you how to do this. Your doctor will also trim your nails once each month during your treatment. Only apply ciclopirox topical solution to your nails and the skin under and around your nails. Be careful not to get the solution on any other areas of the skin or parts of your body, especially in or near your eyes, nose, mouth, or vagina. Do not use nail polish or other nail cosmetic products on nails treated with ciclopirox topical solution. Do not take a bath, shower, or swim for at least 8 hours after applying ciclopirox topical solution. Ciclopirox topical solution may catch fire. Do not use this medication near heat or an open flame, such as a cigarette. To use ciclopirox topical solution, follow these steps: * Be sure that you have trimmed your nails properly before your first treatment. * Use the applicator brush attached to the bottle cap to apply ciclopirox topical solution evenly to all affected nails. Also apply the solution to the underside of the nail and the skin beneath it if you can reach these areas. * Wipe off the bottle cap and neck and replace the cap tightly on the bottle. * Let the solution dry for about 30 seconds before you put on socks or stockings. * When it is time for your next dose, apply ciclopirox topical solution over the medication that is already on your nails. * Once a week, remove all the ciclopirox from your nail(s) with a cotton square or tissue soaked with rubbing alcohol. Then, remove as much of the damaged nail as possible using scissors, nail clippers, or nail files.

Penlac SIDE EFFECTS
Ciclopirox topical solution may cause side effects. Tell your doctor if the following symptom is severe or does not go away: * redness at the place where you applied ciclopirox Some side effects can be serious. The following symptoms are uncommon, but if you experience any of them, call your doctor immediately: * irritation, itching, burning, blistering, swelling, or oozing at the place where you applied ciclopirox * pain at the affected nail(s) or surrounding area * discoloration or change in shape of nail(s) * ingrown nail(s) Ciclopirox topical solution may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

Penlac PRECAUTIONS
Before using ciclopirox topical solution, * tell your doctor and pharmacist if you are allergic to ciclopirox or any other medications. * tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking. Be sure to mention any of the following: inhaled steroids such as beclomethasone (Beconase, Vancenase), budesonide (Pulmicort, Rhinocort), flunisolide (AeroBid); fluticasone (Advair, Flonase, Flovent), mometasone (Nasonex), and triamcinolone (Azmacort, Nasacort, Tri-Nasal); oral medications to treat fungal infections such as fluconazole (Diflucan), itraconazole (Sporanox), ketoconazole (Nizoral), terbinafine (Lamisil) and voriconazole (Vfend); medications for seizures; and steroid creams, lotions, or ointments such as alclometasone (Aclovate), betamethasone (Alphatrex, Betatrex, Diprolene, others), clobetasol (Cormax, Temovate), desonide (DesOwen, Tridesilon), desoximetasone (Topicort), diflorasone (Maxiflor, Psorcon), fluocinolone (DermaSmoothe, Synalar), fluocinonide (Lidex), flurandrenolide (Cordran), halcinonide (Halor), hydrocortisone (Cortizone, Westcort, others), mometasone (Elocon), prednicarbate (Dermatop), and triamcinolone (Aristocort, Kenalog, others). Your doctor may need to change the doses of your medications or monitor you carefully for side effects. * tell your doctor if you have or have ever had an organ transplant, if you have recently had chicken pox, and if you have or have ever had any disease that affects your immune system, such as human immunodeficiency virus (HIV) or acquired immunodeficiency syndrome (AIDS) or severe combined immunodeficiency syndrome (SCID); cancer; cold sores; diabetes; flaky, itchy, or crusty skin; genital herpes (sexually transmitted disease that causes painful blisters on reproductive organs); shingles (painful blisters caused by the chicken pox virus); fungal infections on your skin such as athlete's foot and ringworm (ring-shaped discolored patches of scales and blisters on the skin, hair, or nails); peripheral vascular disease (narrowing of blood vessels in feet, legs, or arms causing numbness, pain, or coldness in that part of the body); or seizures. * tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking ciclopirox, call your doctor. * you should know that you should keep your nails clean and dry during treatment with ciclopirox topical solution. Do not share nail care tools. Use different tools for infected and healthy nails. If your toenails are affected, wear well-fitting, low heeled shoes, and change them change frequently, and do not go barefoot in public areas. Wear protective shoes and gloves when playing sports, using strong cleaners, or during work that might injure or irritate fingernails and toenails.

Penlac DRUG INTERACTIONS
Tell your doctor of all prescription and nonprescription meds you may use, especially of: carbamazepine, narcotic pain relievers (e.g., codeine), drugs used to aid sleep, antidepressants (e.g., SSRI-types such as fluoxetine or fluvoxamine), MAO inhibitors (e.g., furazolidone, linezolid, phenelzine, procarbazine, selegiline, tranylcypromine), psychiatric medicine (e.g., nefazodone), "triptan"-type drugs, anti-anxiety drugs (e.g., diazepam), sibutramine. Also, report use of certain antihistamines (e.g., diphenhydramine) which are also present in many cough-and-cold products. Do not start or stop any medicine without doctor or pharmacist approval.

Penlac OVERDOSE
If overdose is suspected, contact your local poison control center or emergency room immediately.

Penlac NOTES
Do not share Penlac with others. Medical examinations including the nose are generally performed during prolonged use of this product to check for side effects. Inform all your doctors you use (or have used) Penlac.

MISSED DOSE
If you miss a dose, use Penlac as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up.

Penlac STORAGE
Store Penlac at room temperature between 36 and 77 degrees F (2 -25 degrees C) away from light and moisture.